The Alliance for African Partnership (AAP), a consortium of ten leading African universities, a distinguished research network for African research institute, and Michigan State University, is inviting proposals for its Partnerships for Innovative Research in Africa (PIRA) strategic funding program. As a consortium-wide initiative, PIRA is a tiered funding opportunity designed to cultivate and support multidirectional, collaborative research partnerships at any stage of their development, whether they are initiatives to explore and create new relationships or scale existing ones. One of the unique aspects to these grants is the expectation that organizations will establish and develop fair and equitable partnerships from conception to closeout of the project, involving local stakeholders throughout the project, respecting their knowledge and expertise, and taking an adaptive approach that is responsive to the local context. Proposals should outline processes to establish such partnerships. Fair and equitable partnerships must also be established among members of the consortium if multiple organizations are working on the implementation of the project. Proposed partnership activities may entail cooperative research, capacity building initiatives, outreach and/or other activities that align with AAP’s pillars of building bridges, transforming institutions, and transforming lives. Proposals must address at least one of AAP’s priority areas: agri-food systems; water, energy and  environment; culture and society; youth empowerment; education; health and nutrition; and, science, technology, and innovation.